Metabolic Physiology
Glycemic Index
Also known as: GI
A 0-100 scale ranking how rapidly and how high a carbohydrate-containing food raises blood glucose relative to a reference (pure glucose = 100).
Key takeaways
- Glycemic index measures the 2-hour post-meal blood-glucose response curve of a carbohydrate food relative to a reference (pure glucose or white bread).
- Low-GI foods (< 55) raise glucose slowly; high-GI foods (> 70) raise it quickly.
- GI is measured on isolated foods; real-meal GI is modified substantially by fat, protein, fibre, and cooking method.
- GI alone does not predict satiety, body-composition outcomes, or cardiovascular risk reliably — glycemic load and total dietary pattern matter more.
Glycemic index (GI) is a numerical scale from 0 to 100 that ranks carbohydrate-containing foods by how quickly and how high they raise blood glucose in the two hours after eating them. Pure glucose is the reference at 100; white bread is often used as an alternate reference at the same 100 value.
How GI is measured
The standard protocol: 10 fasted subjects eat a test food containing 50 g of available carbohydrate. Blood glucose is measured at standard intervals for 2 hours. The area under the resulting glucose curve (iAUC) is compared to the same person's iAUC after 50 g of pure glucose. Average across subjects gives the GI value for that food.
The GI scale
- Low GI (< 55): most non-starchy vegetables, legumes, most fruits, whole oats, most dairy.
- Medium GI (55–69): whole-grain bread, brown rice, sweet potato, banana.
- High GI (≥ 70): white bread, white rice, instant oats, processed breakfast cereals, jelly beans.
Why real-meal GI diverges from the lab number
GI is measured on isolated foods eaten in a fasted state. Real meals include:
- Fat — slows gastric emptying, reduces post-meal glucose spike.
- Protein — similar effect, plus modest insulin response.
- Fibre — particularly soluble, reduces glucose absorption rate.
- Food form — al-dente pasta has substantially lower GI than overcooked pasta. Whole fruit has lower GI than juiced fruit.
- Ripeness — a ripe banana has higher GI than a green one.
So the "GI of X" number from a published table is a ceiling estimate for that food eaten in isolation. In a mixed meal, the effective GI is usually lower.
Does GI matter for weight and body composition?
Evidence is mixed. Low-GI dietary patterns correlate with improved satiety per calorie in some studies, with no effect in others. For body-composition outcomes in calorie-controlled diets, GI alone is a weak predictor. Total calories, protein intake, and food-environment variables (palatability, processing, energy density) consistently outperform GI as explanatory factors.
Where GI is genuinely useful
- Type 1 and type 2 diabetes management — matching carbohydrate timing and composition to insulin dose or endogenous insulin response.
- Pre-exercise nutrition — low-GI pre-workout for sustained energy, higher-GI during and post-workout for rapid glycogen repletion.
- Continuous glucose monitor (CGM) n=1 tracking — users with CGMs often find that their personal glucose response to specific foods diverges from published GI tables. Personal data beats population averages here.
GI vs glycemic load
GI is a percentage-based comparison; it does not factor in serving size. A high-GI food eaten in a small portion raises glucose less than a medium-GI food eaten in a large portion. Glycemic load (GL = GI × grams of available carbohydrate per serving ÷ 100) corrects for portion and is the more practical metric for real-world dietary assessment.
References
- Jenkins DJ et al.. "Glycemic index of foods: a physiological basis for carbohydrate exchange". American Journal of Clinical Nutrition , 1981 .
- Atkinson FS, Foster-Powell K, Brand-Miller JC. "International tables of glycemic index and glycemic load values: 2008". Diabetes Care , 2008 .
- "Carbohydrates and Blood Sugar". Harvard T.H. Chan School of Public Health — The Nutrition Source .
- Zeevi D et al.. "Personalized nutrition by prediction of glycemic responses". Cell , 2015 .
Related terms
- Carbohydrates The macronutrient composed of sugars, starches, and fibres — yielding 4 kcal per gram and …
- Fiber The non-digestible carbohydrate component of plant foods — effectively contributing 0-2 kc…
- Glycemic Load The portion-corrected version of glycemic index: GL = GI × grams of available carbohydrate…
- Insulin Sensitivity The efficiency with which cells respond to insulin — higher sensitivity means less insulin…